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. 2023 May 19;9:86. doi: 10.1186/s40792-023-01668-x

Table 1.

Summary of complete response cases with nivolumab treatment for Stage IV gastric cancer

References Year Age Sex Initial treatment Metastasis (recurrence) Number of chemotherapy regimens prior to nivolumab Course of nivolumab Post-nivolumab surgery Post nivolumab chemotherapy Adverse events Prognosis
Dai et al. [13] 2022 66 M Palliative surgery Liver 1 8 Hepatectomy None Immune pneumonia 32 months
Toyota et al. [14] 2022 73 M Chemotherapy Liver (invasion) None 5 Distal gastrectomy and hepatectomy S-1 None N/A
Pan et al. [15] 2022 45 M Chemotherapy Liver, lung, lymph nodes 3 5 Total gastrectomy Nivolumab Exfoliative dermatitis eruption 4 years
Takami et al. [16] 2021 70 F Total gastrectomy Peritoneal dissemination, lymph nodes 2 54 None Nivolumab None 7 years
Watanabe et al. [17] 2021 73 M Chemotherapy Liver 2 31 Total gastrectomy None None 43 months
Kumamoto et al. [18] 2021 69 M Chemotherapy Lymph nodes 2 8 Esophagectomy None None Over 12 months
Komo et al. [19] 2021 69 F Chemotherapy Peritoneal dissemination 2 9 None None Immune pneumonia Over 20 months
Matsumoto et al. [9] 2020 63 F Chemotherapy Liver, lung 2 26 Distal gastrectomy Nivolumab None 41 months
Kuhara et al. [20] 2020 60 F Chemotherapy Lymph nodes 2 39 None Nivolumab Rash Over 48 months
Toyota et al. [21] 2020 75 M Chemotherapy Peritoneal dissemination 2 23 Distal gastrectomy None None Over 20 months
Toyota et al. [22] 2020 70 M Chemotherapy Pancreas and spleen (invasion), lymph nodes 2 24 Total gastrectomy with distal pancreatosplenectomy None Rash, gland hypofunction Over 20 months
Kashima et al. [23] 2019 25 M Chemotherapy Lymph nodes 1 48 Total gastrectomy Nivolumab None Over 60 months
Namikawa et al. [24] 2018 77 M Total gastrectomy Spleen, liver 2 16 None Nivolumab None 28 months

N/A: not available