Table 1.
Commonly found quorum quenching enzymes in bacteria.
| Enzyme | Mechanism | Quenching enzyme target | Examples | References |
|---|---|---|---|---|
| AHL Lactonase | Hydrolysis of AHL-lactone bonds | AHL | PON1 (mammalian liver) | [71] |
| QsdR1 (Rhizobium sp. NGR234) | [72] | |||
| QsdA (Rhodococcus erythropolis) | [73] | |||
| AhlS (Solibacillus silvestris) | [74] | |||
| MomL (Pectobacterium carotovorum) | [75] | |||
| AHL-acylase | Deacylation, hydrolysis in amide-bond of AHLs | AHL | QuiP (Pseudomonas aeruginosa PAO1) | [76] |
| AiiD (Ralstonia sp. HJ12B) | [77] | |||
| AiiO (Ochrobactrum sp. A44) | [78] | |||
| AhlM (Streptomyces sp. M664) | [79] | |||
| AHL-oxidase | Catalysis of acyl-chain oxidation | AHL | CYP102A1 (Bacillus megaterium) | [80] |
| AHL-reductase | Conversion of 3-oxo-substituted-AHLto 3-hydroxyl substituted AHLs | AHL | BpiB09 | [81] |
| Quinolone dioxygenase | Catalysis of PQS conversion to N-octanoyl-anthranilic acid and CO | Quinolones | 2-alkyl-3-hydroxy-4(1H)-quinolone 2,4-dioxygenase (Arthrobacter sp.) | [82] |