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(a) Overlay of the crystal structures of native DHP (red, PDB ID: 1EW6)92 and WT-Mb (blue, PDB ID: 5YCE).89 (b) Active sites of native DHP and WT-Mb. The distances between the Nε atoms of the distal His residues and the heme irons in DHP, Mb, and the G65T and G65I Mb variants are summarized in the table on the right.
