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. Author manuscript; available in PMC: 2023 May 20.
Published in final edited form as: Chem Rev. 2022 Jul 11;122(14):11974–12045. doi: 10.1021/acs.chemrev.2c00106

Figure 69.

Figure 69.

Model of Rosetta design on the crystal structure of the Ir complex in WT-hCA II (PDB ID: 3ZP9). Designed backbone-stabilizing H-bonds are represented as green dashed lines. Reprinted with permission from ref 597. Copyright 2015 American Chemical Society.