Table 4.

Correlation between pro-inflammatory cytokines with depression score in patients with bipolar disorder

	Groups	n	IL-6		TNF-α		hs-CRP
			R	P	R	P	R	P
Before	Omega-3	30	0.385	0.032	0.421	0.019	0.682	<0.001
Before	Placebo	30	0.521	<0.001	0.512	<0.001	0.711	<0.001
After	Omega-3	30	0.414	0.012	0.365	0.039	0.811	<0.001
After	Placebo	30	0.445	<0.001	0.551	<0.001	0.351	0.039

The results are reported as correlation coefficient. IL-6=Interleukin-6; TNF-α=Tumor necrosis factor-α; hs-CRP=High-sensitivity C-reactive protein