Table 1.

Clinical characteristics of the patients included in this cohort

	All patients - N=415	Patients without auto-Abs in BAL - N=361	Patients with auto-Abs in BAL - N=54	P-value*	Missing data
Age (years)	60 (50—67)	59 (50—67)	63 (57 – 71)	0.0045	10 (2%)
Male	277 (69%)	241 (68%)	36 (73%)	0.46	13 (3%)
Death	202 (51%)	172 (50%)	30 (60%)	0.19	19 (5%)
Length of ICU stay (days)	28 (16 – 47)	29 (16 – 47)	24 (12 – 48)	0.69	209 (50%)
Duration of invasive ventilation (days)	25 (13 – 42)	26 (14 – 42)	24 (12 – 45)	0.79	216 (52%)
Time from symptom onset to BAL (days)	15 (9 – 21)	15 (9 – 21)	14 (10 – 24)	0.79	330 (80%)
Time from ICU admission to BAL (days)	7 (4—12)	7 (4—13)	6 (4—10)	0.22	214 (52%)

Data are reported as N, N (%), or median (interquartile range); *Patients with autoantibodies against type I IFNs (auto-Abs) in bronchoalveolar lavage (BAL) were compared with those without such antibodies, in t- or chi-squared tests, with a P-value < 0.05 considered significant