Table 1.
Single nucleotide polymorphisms identified in pfk13 gene in samples collected in Niassa, Manica and Maputo, Mozambique duiring 2021
| Codon | Type of mutation | Reference» mutant | Study site | n/N |
|---|---|---|---|---|
| G449R | NS | ggt» cgt | Manica | 1/98 |
| V454E | NS | gta» gaa | Niassa | 1/100 |
| E455Q | NS | gaa» caa | Maputo | 1/100 |
| S459S | S | tcg» tcc | Manica | 3/98 |
| D464Y | NS | gat» cat | Manica | 1/98 |
| D464H | NS | gat» cat | Niassa | 1/100 |
| C469C* | S | tgc» tgt | Manica | 3/98 |
| Maputo | 2/100 | |||
| W470R | NS | tgg» agg | Manica | 2/98 |
| Niassa | 3/100 | |||
| Maputo | 1/100 | |||
| V494L | NS | gtt» ctt | Niassa | 1/100 |
| E509D | NS | aga» aaa | Manica | 1/98 |
| C532W | NS | tgt» tgg | Niassa | 1/100 |
| I543S | NS | att» agt | Maputo | 1/100 |
| G548G | S | ggg» ggt | Manica | 1/98 |
| G549G | S | tct» ttt | Manica | 1/98 |
| A578S | NS | gct» tct | Niassa | 1/100 |
| A578P | NS | gct» cct | Niassa | 1/100 |
| V581A | NS | gtt» gct | Niassa | 1/100 |
| L598L | S | tta» cta | Manica | 1/98 |
| Q654H | NS | caa» cac | Manica | 1/98 |
| Q661H* | NS | caa» cac | Maputo | 1/100 |
| L663I | NS | caa» cac | Maputo | 1/100 |
n: number of samples containing mutant allele; N: number of samples sequenced at locus; NS: non-synonymous SNP; S: synonymous SNP; * has previously been reported