Table 4.
Glucose Testing and Hemoglobin A1C Interpretation
| Normal | Prediabetes | Diabetes |
|---|---|---|
| FPG <100 mg/dL | IFG FPG ≥100 to 125 mg/dL |
FPG ≥126 mg/dL |
| 2-h PG <140 mg/dL | IGT 2-h PG ≥140 to 199 mg/dL |
2-h PG ≥200 mg/dL Random PG ≥200 mg/dL + symptoms |
| A1C <5.5% | 5.7% to 6.4% For screening of prediabetesa |
≥6.5% Secondaryb |
Abbreviations: A1C = hemoglobin A1c; FPG = fasting plasma glucose; h = hour; IFG = impaired fasting glucose; IGT = impaired glucose tolerance; PG = plasma glucose
A1C should be used only for screening prediabetes. The diagnosis of prediabetes, which may manifest as either IFG or IGT, should be con rmed with glucose testing.
Glucose criteria (ie, FPG or 2-h glucose after a 75-g oral glucose load) are preferred for the diagnosis of diabetes mellitus (DM). The same testdPG or A1C measurementd—should be repeated on a different day to confirm the diagnosis of DM. Two abnormal test results from the same sample confirm the diagnosis of DM. A glucose level ≥200 mg/dL in the presence of DM symptoms does not need to be confirmed.