Table 6.

Glycemic Targets for Persons with Diabetes Mellitus

Parameter	Treatment goal
Glucose
A1C, %	Individualize on the basis of age, comorbid conditions, duration of disease; in general, ≤6.5 for most; closer to normal for healthy; less stringent for those at greater risk for hypoglycemia and/or adverse consequences from hypoglycemia; longer duration of diabetes; shorter life expectancy; comorbidities especially established vascular complications
FPG, mg/dL	<110
2-h PPG, mg/dL	<140
Inpatient hyperglycemia: glucose, mg/dL	140 to 180
Weight
Weight loss	Reduce weight by >5% to ≥10%; avoid weight gain
Diabetes type	Glucose range a,179	Recommendations (% of readings)
T1D and T2D	<54 mg/dL (<3.0 mmol/L)	<1%
	<70 mg/dL (<3.9 mmol/L)	<4%
	70 to 180 mg/dL (3.9 to 10.0 mmol/L)	>70%
	>180 mg/dL (>10.0 mmol/L)	<25%
	>250 mg/dL (>13.9 mmol/L)	<5%
Pregnancy with T1D	<54 mg/dL (<3.0 mmol/L)	<1%
	<63 mg/dL (<3.5 mmol/L)	<4%
	63 to 140 mg/dL (3.5 to 7.8 mmol/L)	>70%
	>140 mg/dL (>7.8 mmol/L)	<25%
Pregnancy with gestational or T2D	63 to 140 mg/dL (3.5 to 7.8 mmol/L)	>90%

Abbreviations: A1C = hemoglobin A1c; FPG = fasting plasma glucose; PPG = postprandial glucose; T1D = type 1 diabetes; T2D = type 2 diabetes

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