Table 3. Plasma differential metabolite pathway analysis between the malignant mesothelioma and healthy control groups.
| Pathway name | Totala | Hitsb | p-value | −log10P | Rich factorc |
|---|---|---|---|---|---|
| Alanine, aspartate and glutamate metabolism | 28 | 3 | 2.53E−03 | 2.597 | 0.284 |
| Glyoxylate and dicarboxylate metabolism | 32 | 3 | 3.73E−03 | 2.428 | 0.103 |
| Arginine and proline metabolism | 38 | 3 | 6.11E−03 | 2.214 | 0.133 |
| Butanoate metabolism | 15 | 2 | 9.70E−03 | 2.013 | 0.032 |
| Histidine metabolism | 16 | 2 | 1.10E−02 | 1.958 | 0.221 |
| beta-Alanine metabolism | 21 | 2 | 1.87E−02 | 1.728 | 0.000 |
| Pentose phosphate pathway | 22 | 2 | 2.05E−02 | 1.689 | 0.047 |
Notes:
a
Number of total metabolites in pathway.
b
Number of metabolites detected.
c
Ratio of detected metabolites in the pathway. Result from online tool (https://www.metaboanalyst.ca).