Table 3.
Association Between Preterm Birth and Sexually Transmitted Infections in Pregnancy From Univariable Log-Binomial Generalized Estimating Equation Modelsa
| STI | PTB (n = 291), No. (%) | Term Delivery (n = 1855), No. (%) | RR (95% CI) | P Value |
|---|---|---|---|---|
| CT positive | 21 (12) | 148 (88) | 0.91 (.60–1.38) | .67 |
| CT negative (missing n = 41 [2%]) | 267 (14) | 1669 (86) | ||
| NG positive | 5 (10) | 45 (90) | 0.74 (.32–1.69) | .47 |
| NG negative (missing n = 42 [2%]) | 281 (14) | 1773 (86) | ||
| Syphilis positive | 11 (21) | 41 (79) | 1.60 (.90–2.83) | .11 |
| Syphilis negative (missing n = 68 [3%]) | 266 (13) | 1760 (87) | ||
| TV positive | 31 (14) | 185 (86) | 1.04 (.73–1.48) | .82 |
| TV negative (missing n = 642 [30%]) | 176 (14) | 1112 (86) | ||
| Any STI in pregnancy | 58 (15) | 335 (85) | 1.08 (.81–1.44) | .60 |
| No STI in pregnancy (missing n = 604 [28%]) | 154 (13) | 995 (87) | ||
| No. of STIs | ||||
| 0 | 154 (13) | 995 (87) | Ref | .17 |
| 1 | 45 (17) | 223 (83) | 1.23 (.90–1.67) | |
| ≥2 (missing n = 659 [31%]) | 6 (9) | 64 (91) | 0.66 (.31–1.39) |
Abbreviations: CI, confidence interval; CT, Chlamydia trachomatis; NG, Neisseria gonorrhoeae; PTB, preterm birth; Ref, reference group; RR, risk ratio; STI, sexually transmitted infection; TV, Trichomonas vaginalis.
a
CT, NG, syphilis, TV, any STI, and number of STIs were each modeled separately.