Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Graphical summary of the major pharmacokinetic processes determining the disposition of mAbs and their modulation in newborns and infants. The gear symbol indicates elimination processes. Figure from Z. Temrikar et al Paediatr Drugs 2020 [22]. Abbreviations: ADA, anti-drug antibody; FcRn, neonatal Fc receptor; Ig, immunoglobulin; IM, intramuscular; IV, intravenous; mAb, monoclonal antibody; SC, subcutaneous.
