Table 1.
Characteristics of 612 pediatric trials published in leading general pediatric and medical journalsa
| Trial Characteristics | N (%) |
|---|---|
| Participant age group in article | |
| All pediatric age groups | 91 (14.9) |
| Neonate (0-30 days) | 115 (18.8) |
| Infants and toddlers (31 days-3 years) | 92 (15.0) |
| Pre-school and school age (4-12 years) | 138 (22.5) |
| Adolescent (13-18 years) | 176 (28.8) |
| Trial allocation | |
| Randomized | 574 (93.8) |
| Not randomized | 38 (6.2) |
| Participant enrollment | |
| <100 | 172 (28.1) |
| 100-499 | 284 (46.4) |
| ≥500 | 156 (25.5) |
| Trial intervention | |
| Behavioral | 244 (39.9) |
| Drug/biologic/dietary supplement | 239 (39.1) |
| Device/procedure | 75 (12.3) |
| Screening/Referral/Health services | 54 (8.7) |
| Funding source | |
| Public | 342 (55.9) |
| Private | 112 (18.3) |
| Public and Private | 128 (20.9) |
| None Reported | 30 (4.9) |
| Participant preferred language reported | 181 (29.6) |
| Socioeconomic factor(s) reported | 293 (47.9) |
| Sex reported (N=282) b | 272 (96.1) |
| Sexual orientation reported (N=282) b | 9 (1.5) |
| Gender identity reported (N=282) b | 2 (0.7) |
a
JAMA Pediatrics, Lancet Child & Adolescent Health, Pediatrics, Journal of Adolescent Health, the Journal of Pediatrics, New England Journal of Medicine, Lancet, JAMA, BMJ, and PLoS Medicine
b
There were 282 trials that enrolled school age or adolescent participants.