Table 1B.

Histological classification kidney graft biopsies evaluated using the Banff score.

		Normal/non-specific			Fibrotic
	Banff lesion scores	KUT023	KUT060	KUT081	KUT040	KUT065	KUT076	KUT088	KUT100
Acute	Glomerulitis (g)	0	0	0	0	0	0	0	0
	Interstitial inflammation (i)	0	0	0	0	0	1	2	0
	Peritubular capillaritis (ptc)	0	0	0	0	0	1	0	0
	Tubulitis (t)	0	0	0	0	0	2	2	1
	Intimal arteritis (v)	0	0	0	0	0	0	0	0
Chronic	Arteriolar hyalinosis (ah)	0	0	0	2	1	0	1	1
	Glomerular basement membrane double contours (cg)	0	0	0	0	0	0	0	0
	Interstitial fibrosis (ci)	0	0	0	2	2	2	2	3
	Peritubular capillary basement membrane multilayering (cptc)	0	0	0	0	0	0	0	0
	Tubular atrophy (ct)	0	0	1	2	2	2	2	3
	Vascular fibrous intimal thickening (cv)	0	0	0	2	2	3	2	3
	Inflammation in areas of interstitial fibrosis and tubular atrophy (iIFTA)	0	0	0	0	0	2	1	0
	Total inflammation (ti)	0	0	0	1	1	1	0	0
	Mesangial matrix expansion (mm)	1	0	0	1	0	0	1	0
	BK virus (SV40 large T antigen)	-	-	-	-	-	-	-	-
	C4d	-	-	-	-	-	-	-	-
	Global glomerulosclerosis (%)	<5	0	<5	2	17	<5	8	16

All biopsies were assessed using light (LM), immunofluorescence (IF), and electron microscopy (EM) and reported independently by two transplant pathologists using Banff 2019 update¹ of the Banff 97 classification.² All biopsies were negative for peritubular capillary staining for complement factor 4 fragment d (C4d) tested by immunofluorescence. All biopsies were negative for BK virus (SV40 large T antigen, immunoperoxidase staining).

KUT023: LM: 72 non-sclerotic glomeruli, IF: up to 13 non-sclerotic glomeruli; KUT060: LM: 37 non-sclerotic glomeruli, IF: up to 10 non-sclerotic glomeruli; KUT081: LM: 12 non-sclerotic glomeruli, IF: up to 10 non-sclerotic glomeruli; KUT040: LM: 17 non-sclerotic glomeruli, 2 globally sclerotic, IF: up to 10 non-sclerotic glomeruli; KUT065: LM: 43 non-sclerotic glomeruli, 5 globally sclerotic IF: 15 non-sclerotic glomeruli, 8 globally sclerotic; KUT076: LM: 39 non-sclerotic glomeruli, 4 globally sclerotic IF: up to 10 non-sclerotic glomeruli; KUT088: 39 non-sclerotic glomeruli, 2 globally sclerotic IF: 8 non-sclerotic glomeruli; KUT100: 46 non-sclerotic glomeruli, 14 globally sclerotic IF: up to 10 non-sclerotic glomeruli.