Table 1.
Patient No. | Sex | Germline FLCN mutation | Mutation type | Sample No. | Age at surgery | Histology | Size (mm) | Stage | |
---|---|---|---|---|---|---|---|---|---|
1 | F42 | female | c.1285dupC | Frameshift | F42-T1 | 49 | ChRCC | 30 | T1a |
F42-T2 | 49 | ChRCC | 13 | T1a | |||||
F42-T3 | 53 | ChRCC | 20 | T1a | |||||
2 | F43 | male | c.1285dupC | Frameshift | F43-T1 | 54 | ChRCC | 24 | T1a |
3 | F59 | male | c.1528_1530delGAG | Amino acid deletion | F59-T1 | 50 | ChRCC | 43 | T1b |
F59-T2 | 50 | ChRCC | 14 | T1a | |||||
F59-T8 | 50 | HOCT | 32 | T1a | |||||
F59-T11 | 50 | ChRCC | 10 | T1a | |||||
F59-T12 | 50 | ChRCC | 8 | T1a | |||||
4 | F107 | male | c.1347_1353dupCCACCCT | Frameshift | F107-T1 | 56 | Clear cell | 42 | T3b |
5 | F123 | female | c.1285dupC | Frameshift | F123-TR1 | 34 | HOCT | 27 | T1a |
6 | F124 | male | c.1285dupC | Frameshift | F124-T1 | 64 | HOCT | 26 | T1a |
7 | F133 | female | c.1285dupC | Frameshift | F133-T1 | 66 | Unclassified | 30 | T1a |
F133-T2 | 66 | ChRCC | 10 | T1a | |||||
8 | F135 | female | c.1347_1353dupCCACCCT | Frameshift | F135-T1 | 40 | HOCT | 7 | T1a |
9 | F192 | female | c.404delC | Frameshift | F192-T1 | 54 | ChRCC | 15 | T1a |