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. 2023 May 8;14:1153462. doi: 10.3389/fendo.2023.1153462

Table 2.

Prevalence of metabolic syndrome and its components in US adults with different urinary iodine concentration.

Variable Prevalence (%) of Metabolic Syndrome and Its Components
Total Normal UIC
(100-299ug/L)
Low UIC (<100ug/L) High UIC
(300-399ug/L)
Very high UIC
(≥400ug/L)
P-value
All participants
MetS 3200 (27.7) 1627 (27.0) 962 (22.2) 262 (32.6) 349 (29.4) < 0.001
MetS.Diabetes 3550 (30.7) 1831 (29.7) 1129 (25.3) 285 (32.8) 305 (24.7) < 0.001
MetS.low-HDL-C 3571 (30.9) 1741 (30.3) 1151 (26.6) 293 (35.5) 386 (34.0) < 0.001
MetS.TG 4248 (36.8) 2103 (37.1) 1298 (31.6) 350 (43.5) 497 (44.0) < 0.001
MetS.obesity 6668 (57.8) 3284 (58.2) 2192 (53.6) 506 (61.1) 686 (59.5) < 0.001
MetS.hypertension 2023 (17.5) 964 (15.9) 707 (16.1) 149 (16.2) 203 (15.6) 0.99
Female
MetS 1724 (30.0) 857 (28.8) 566 (22.3) 118 (28.9) 183 (31.1) < 0.001
MetS.Diabetes 1555 (27.1) 795 (26.7) 533 (20.8) 104 (27.4) 123 (19.8) 0.006
MetS.low-HDL-C 2102 (36.6) 982 (34.7) 751 (30.2) 147 (35.6) 222 (41.5) 0.001
MetS.TG 1856 (32.3) 908 (31.5) 598 (25.9) 141 (38.1) 209 (38.9) < 0.001
MetS.obesity 3994 (69.6) 1896 (68.8) 1438 (61.2) 275 (71.6) 385 (71.7) < 0.001
MetS.hypertension 939 (16.4) 447 (16.1) 351 (14.5) 65 (16.1) 76 (12.3) 0.322
Male
MetS 1476 (25.4) 770 (25.4) 396 (21.9) 144 (35.6) 166 (28.0) < 0.001
MetS.Diabetes 1995 (34.4) 1036 (32.5) 596 (30.8) 181 (37.2) 182 (28.7) 0.125
MetS.low-HDL-C 1469 (25.3) 759 (26.1) 400 (22.3) 146 (35.4) 164 (27.7) < 0.001
MetS.TG 2392 (41.2) 1195 (42.3) 700 (38.7) 209 (48.0) 288 (48.2) 0.004
MetS.obesity 2676 (46.1) 1388 (48.0) 754 (44.0) 231 (52.4) 301 (49.5) 0.05
MetS.hypertension 1084 (18.7) 517 (15.9) 356 (18.0) 84 (16.3) 127 (18.3) 0.484

UIC, urinary iodine concentration. MetS, metabolic syndrome,

MetS.Diabetes, History of diabetes, Glycosylated hemoglobin (HbA1c) > 6.5%, fasting glucose (mmol/L) ≥ 7.0, or medication used to treat diabetes;

MetS.obesity, Waist Circumference (WC) ≥ 102 cm in men or ≥ 88 cm in women;

MetS.hypertension, blood pressure ≥ 130/85 mmHg or hypertension history or treatment with antihypertensive medication;

MetS.low-HDL-C, HDL-C < 40 mg/dL for men and < 50 mg/dL for women or use of anti-lipid abnormalities;

MetS.TG, TG ≥ 150 mg/dL, or pharmacological treatment of TG. The prevalence of metabolic syndrome components according to the urinary iodine concentration was compared using Rao Scott’s χ2 test.