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. 2023 May 8;14:1133991. doi: 10.3389/fendo.2023.1133991

Table 2.

Association of blood lactate with the prevalence of MAFLD.

B statistic OR 95% CI p value
Without metformin
Model 1 0.394 1.482 1.344-1.635 <0.001
Model 2 0.372 1.451 1.312-1.605 <0.001
Model 3 0.341 1.406 1.263-1.565 <0.001
Model 4 0.289 1.335 1.197-1.488 <0.001
Model 5 0.270 1.311 1.144-1.501 <0.001
Model 6 0.166 1.181 1.010-1.381 0.037
Metformin
Model 1 0.422 1.525 1.404-1.658 <0.001
Model 2 0.449 1.566 1.438-1.706 <0.001
Model 3 0.451 1.570 1.434-1.719 <0.001
Model 4 0.418 1.519 1.386-1.665 <0.001
Model 5 0.410 1.506 1.341-1.692 <0.001
Model 6 0.320 1.378 1.210-1.569 <0.001

Model 1: unadjusted.

Model 2: Adjusted for age, sex, and DD.

Model 3: Further adjustment for obesity, smoking status, and alcohol drinking.

Model 4: Further adjustment for use of LLD, IIAs, and insulin sensitizers.

Model 5: Further adjustment for WC, WHR, and BMI.

Model 6: Further adjustment for TC, HDL-C, LDL-C, TG, eGFR, SUA, UAE, FPG, 2-h PPG, HbA1c, CRP, FCP, and 2-h PCP.