Table 1.
Some of the important studies of uveitis associated with SpA.
Study [Reference] | Study Design | Diagnosis/Number of patients | Study outcomes |
---|---|---|---|
Vale et al., 20186 | Observational retrospective study | SpA/153 | Uveitis predominantly occurred in men, and more frequently in HLA-B27 positive patients |
Mitulescu et al., 20187 | Retrospective study | SpA/67 | Patients with AAU and inflammatory back pain should be referred to a rheumatology unit. |
Ninan et al., 20178 | Hospital based cross sectional | Seronegative /SpA | Uveitis percentage was 16.3%, AS was commonest occurring in 69.3% and 78.3% patients were HLA-B27 positive |
Das et al., 201510 | Retrospective study | Uveitis of varying etiologies/343 | Changing pattern of uveitis in a tertiary institute was reported with highest number of HLA-B27 associated uveitis. |
Lee et al., 201711 | Retrospective, interventional case series | AS/91 | Men preponderance (70%), average onset in the fourth decade, and unilateral manifestation (87.9%) was observed |
Bouzid et al. 202031 | Retrospective study | SpA/101 | First-line sulfasalazine reduced uveitis relapses |
van Denderen et al., 201434 | Randomized controlled trial | AS/77 | Adalimumab treatment. significantly reduced the number of acute uveitis attacks, and the number of attacks per patient |
Rudwaleit et al., 201637 | Randomized, double-blind and placebo-controlled RAPID-axSpA (NCT01087762) | axial SpA/218 | Certolizumab Pegol reduced uveitis flares |
Calvo-Río et al., 201638 | Multi-center randomized trial | SpA/15 | Golimumab is predicted to be useful therapeutic option in refractory SpA-related uveitis |