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. 2023 Mar 31;34(1):24–29. doi: 10.31138/mjr.34.1.24

Table 1.

Some of the important studies of uveitis associated with SpA.

Study [Reference] Study Design Diagnosis/Number of patients Study outcomes
Vale et al., 20186 Observational retrospective study SpA/153 Uveitis predominantly occurred in men, and more frequently in HLA-B27 positive patients
Mitulescu et al., 20187 Retrospective study SpA/67 Patients with AAU and inflammatory back pain should be referred to a rheumatology unit.
Ninan et al., 20178 Hospital based cross sectional Seronegative /SpA Uveitis percentage was 16.3%, AS was commonest occurring in 69.3% and 78.3% patients were HLA-B27 positive
Das et al., 201510 Retrospective study Uveitis of varying etiologies/343 Changing pattern of uveitis in a tertiary institute was reported with highest number of HLA-B27 associated uveitis.
Lee et al., 201711 Retrospective, interventional case series AS/91 Men preponderance (70%), average onset in the fourth decade, and unilateral manifestation (87.9%) was observed
Bouzid et al. 202031 Retrospective study SpA/101 First-line sulfasalazine reduced uveitis relapses
van Denderen et al., 201434 Randomized controlled trial AS/77 Adalimumab treatment. significantly reduced the number of acute uveitis attacks, and the number of attacks per patient
Rudwaleit et al., 201637 Randomized, double-blind and placebo-controlled RAPID-axSpA (NCT01087762) axial SpA/218 Certolizumab Pegol reduced uveitis flares
Calvo-Río et al., 201638 Multi-center randomized trial SpA/15 Golimumab is predicted to be useful therapeutic option in refractory SpA-related uveitis