TABLE 3.
Adjusted a hazard ratios for all‐cause dementia and dementia subtypes by history of hypertensive disorders of pregnancy
| History of HDP | All‐cause dementia | Vascular dementia | Alzheimer's disease | Other/unspecified dementia | |||||
|---|---|---|---|---|---|---|---|---|---|
| n | HR (95% CI) | n | HR (95% CI) | n | HR (95% CI) | n | HR (95% CI) | ||
| Overall | Exposed | 827 | 1.37 (1.26, 1.50) | 55 | 1.64 (1.19, 2.26) | 178 | 1.04 (0.87, 1.24) | 594 | 1.49 (1.34, 1.65) |
| Unexposed | 1591 | 1 [Reference] | 97 | 1 [Reference] | 401 | 1 [Reference] | 1098 | 1 [Reference] | |
| Attained age by end of follow‐up | |||||||||
| <65 years | Exposed | 100 | 1.87 (1.49, 2.34) | 9 | 2.70 (1.01, 7.17) | 12 | 2.01 (0.99, 4.08) | 79 | 1.77 (1.38, 2.26) |
| Unexposed | 107 | 1 [Reference] | 5 | 1 [Reference] | 9 | 1 [Reference] | 93 | 1 [Reference] | |
| ≥65 years | Exposed | 727 | 1.30 (1.19, 1.43) | 46 | 1.41 (0.98, 2.04) | 166 | 0.99 (0.83, 1.19) | 515 | 1.44 (1.28, 1.61) |
| Unexposed | 1484 | 1 [Reference] | 92 | 1 [Reference] | 389 | 1 [Reference] | 1003 | 1 [Reference] | |
Abbreviations: CI, confidence interval; HDP, hypertensive disorder of pregnancy; HR, hazard ratio.
a
Adjusted for maternal age, birth year, and parity (1, 2, 3, 4, ≥5) at the time of the index pregnancy.