TABLE 4.
Adjusted a hazard ratios for all‐cause dementia and dementia subtypes by history of hypertensive disorders of pregnancy subtypes
| History of HDP | All‐cause dementia | Vascular dementia | Alzheimer's disease | Other/unspecified dementia | |||||
|---|---|---|---|---|---|---|---|---|---|
| n | HR (95% CI) | n | HR (95% CI) | n | HR (95% CI) | n | HR (95% CI) | ||
| Preeclampsia/eclampsia | Exposed | 827 | 1.38 (1.26, 1.50) | 55 | 1.58 (1.11, 2.24) | 178 | 1.04 (0.87, 1.24) | 594 | 1.51 (1.36, 1.68) |
| Unexposed | 1596 | 1 [Reference] | 97 | 1 [Reference] | 401 | 1 [Reference] | 1098 | 1 [Reference] | |
| Gestational hypertension | Exposed | 75 | 1.36 (1.03, 1.79) | 7 | 2.75 (0.90, 8.40) | 16 | 1.18 (0.52, 2.68) | 51 | 1.31 (0.96, 1.80) |
| Unexposed | 132 | 1 [Reference] | 8 | 1 [Reference] | 28 | 1 [Reference] | 97 | 1 [Reference] | |
Abbreviations: CI, confidence interval; HDP, hypertensive disorder of pregnancy; HR, hazard ratio.
aAdjusted for maternal age, birth year, and parity (1, 2, 3, 4, ≥5) at the time of the index pregnancy.