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. 2023 May 18;13(5):e063026. doi: 10.1136/bmjopen-2022-063026

Table 3.

MID values of knee osteoarthritis outcome tools derived using the anchor method

Outcome tools Score Median Minimum Maximum Number of estimates Study
KOOS-pain 100=best 11.8 4 17 13 Mills, 2016; Mostafaee, 202115 39
KOOS-activities of daily living 100=best 2.5 −1.5 15.5 7 Mills, 2016; Mostafaee, 202115 39
KOOS-quality of life 100=best 6.5 3 12.5 7 Mills, 2016; Mostafaee, 202115 39
KOOS-sports/recreation 100=best 17.5 1 Mostafaee, 202139
KOOS-symptoms 100=best 12.5 1 Mostafaee, 202139
KOS-activities of daily living 100=best 6.4 2.2 10.6 6 Williams, 201242
LEFS 100=best 6.9 0.6 15.6 6 Williams, 201242
PROMIS Short Forms-physical function* 100=worst 4.5 5.3 NR Lee, 201744
PROMIS Short Forms-pain interference* 100=worst 4.2 4.2 NR Lee, 201744
PROMIS Short Forms-depression* 100=worst 6 6.2 NR Lee, 201744
PROMIS Short Forms- anxiety* 100=worst 4.5 6.6 NR Lee, 201744
WOMAC-pain 100=best 8.7 7.1 21 3 Angst, 201837
WOMAC-function 100=best 14.5 11.3 14.9 3 Angst, 201837
WOMAC-stiffness 100=best 20.2 16.2 23.8 3 Angst, 201837
WOMAC-standing/walking 100=best 8.1 5.9 10.2 2 Angst, 201837
WOMAC-total 100=best 6.8 1.6 16.8 8 Williams, 2012;
Hmamouchi, 201238 42
SF-36-bodily pain 100=best 9.3 8.2 10.4 2 Angst, 201837
SF-36-physical function 100=best 4.0 3.8 4.2 2 Angst, 201837
SF-36-role-physical 100=best 8.5 7.5 9.5 2 Angst, 201837
SF-36-vitality 100=best 4.5 4.16 4.9 2 Angst, 201837
SF-36-social function 100=best 4.8 2.6 7.0 2 Angst, 201837
SF-36-mental health 100=best 4.1 2.9 5.2 2 Angst, 201837
SF-36-general health 100=best 6.6 6 7.2 2 Angst, 201837
Estimates based on low-quality studies
DAP 100=worst 24 1 Klokker, 201636
ICOAP-pain 100=worst 7.8 1 Harris, 201335
KOOS-PS 100=worst 7.8 1 Harris, 201335
OKS-pain 100=best 14.3 1 Harris, 201335
OKS-function 100=best 9.5 1 Harris, 201335
OKS-summary 100=best 6.4 1 Harris, 201335

All the scores are from 0 to 100.

The median estimates are shaded in blue.

Estimates based on low-quality studies are shaded in grey.

*Estimates were reported as a range.

DAP, Dynamic Weight-Bearing Assessment of Pain; ICOAP, Intermittent and Constant Osteoarthritis Pain; KOOS, Knee injury and Osteoarthritis Outcome Score; KOOS-PS, Knee injury and Osteoarthritis Outcome Score Physical Function Short form; KOS, Knee Outcome Survey; LEFS, Lower Extremity Functional Scale; MID, minimal important difference; NR, not reported; OA, osteoarthritis; OKS, Oxford Knee Score; PROMIS, Patient-Reported Outcome Measurement Information SystemS; SF-36, 36-item Short Form health survey; WOMAC, Western Ontario and McMaster Universities Arthritis Index.