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. 2023 May 22;42(6):112532. doi: 10.1016/j.celrep.2023.112532

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© 2023 The Authors

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Functional verification of N460 and F486 mutations influencing the neutralization susceptibility of SARS-CoV-2 variants to VacBB-551

The neutralization of VacBB-551 against the WT-related (A), BA.2-related (B), BA.2.75-related (C), BQ.1.1-related (D), and XBB.1-related (E) mutated pseudoviruses. Fold changes of neutralization (IC₅₀) are calculated on mean values of two independent experiments. One representative curve is presented here. “-” represents decreased neutralization, and “+” represents increased neutralization.