Table 2.
Alterations to Immunosuppressive Agents, Segmented by Total Drug Suspension or Dose Reduction
| Characteristic | N | Overall N = 234* |
Survived N = 186* |
Dead N = 48* |
P Value† |
|---|---|---|---|---|---|
| TAC Reduction | 194 | 31 (16%) | 22 (14%) | 9 (22%) | .2 |
| TAC Suspension | 194 | 30 (15%) | 14 (9.1%) | 16 (40%) | < .001 |
| MFS Reduction | 138 | 6 (4.3%) | 4 (3.9%) | 2 (5.7%) | .6 |
| MFS Suspension | 138 | 70 (51%) | 48 (47%) | 22 (63%) | .10 |
| EVR Reduction | 42 | 0 (0%) | 0 (0%) | 0 (0%) | - |
| EVR Suspension | 42 | 8 (19%) | 6 (18%) | 2 (25%) | .6 |
| PRED Reduction | 18 | 0 (0%) | 0 (0%) | 0 (0%) | - |
| PRED Suspension | 18 | 3 (17%) | 0 (0%) | 3 (50%) | .025 |
| AZA Reduction | 5 | 0 (0%) | 0 (0%) | 0 (0%) | - |
| AZA Suspension | 5 | 3 (60%) | 1 (33%) | 2 (100%) | .4 |
| CsA Reduction | 10 | 0 (0%) | 0 (0%) | 0 (NA%) | - |
| CsA Suspension | 10 | 4 (40%) | 4 (40%) | 0 (NA%) | > .9 |
| Any partial or total supension to Imunossupression | 222 | 121 (55%) | 84 (48%) | 37 (80%) | < .001 |
Values are displayed as “count (percent).”Bolded = significance (p > 0.05).
AZA = Azathioprine; CsA = Cyclosporine A; EVR = Everolimus; MFS = Mycophenolate Sodium; PRED = Prednisone; Tac = Tacrolimus.
⁎
n (%).
†
Pearson's χ2 test test; Fisher's exact test.