Table 1.
Definitions of Long COVID-19.
| Name | Symptoms/ clinical manifestation | Time after COVID-19 | COVID-19 severity | Reference |
|---|---|---|---|---|
| Post COVID-19 condition/syndrome | fatigue, shortness of breath, cognitive dysfunction or other symptoms affecting everyday functioning | > 3 months, lasting at least 2 months | mild-severe | WHO, 2021 https://www.who.int/publications/i/item/WHO-2019-nCoV-Post_COVID-19_condition-Clinical_case_definition-2021.1 |
| fatigue, exertion intolerance, partly meeting the criteria for ME/CFS | 4–15 months | mild-moderate | [91] | |
| fatigue, exertion intolerance, partly meeting the criteria for ME/CFS | 7–19 months | mild-moderate | [86] | |
| respiratory symptoms, pulmonary abnormalities | 3–6 months | severe | [94] | |
| Mainly cognitive and neurological symptoms | > 3 months | na | [84] | |
| Post-acute sequelae of COVID-19 (PASC) | one or more of the following: constitutional, respiratory, cardiopulmonary, gastrointestinal, genitourinary, reologic, rash, musculoskeletal symptoms, trouble sleeping | > 3 months | mild-severe | [78] |
| respiratory, gastrointestinal, neurological symptoms, anosmia/dysgeusia | 2–3 months | mild-severe | [20] | |
| pulmonary and extrapulmonary symptoms | 2–3 months | severe | [96] | |
| fatigue, respiratory, digestive, neurological, skin and mucous membrane, circulation symptoms | > 1 months | mild | [76] | |
| different symptoms including fatigue, dyspnea, respiratory, body aches | > 1 months | mainly mild-moderate | [79] | |
| respiratory symptoms, interstitial lung changes | 3–12 months | mild-severe | [95] | |
| pulmonary and extrapulmonary symptoms | 2–3 months | severe | [96] | |
| According to WHO case definition | > 6 months | mild-severe (mainly hospitalized) | [97] | |
| Long COVID | fatigue, dyspena, chest pain | > 4 months | mild-severe | [77] |
| breathing difficulties/breathlessness, fatigue/malaise, chest/throat pain, anxiety/depression, headache, myalgia, other pain, cognitive, abdominal symptoms | 3–6 months | mild-severe | [71] | |
| 33 symptoms based on WHO case definition for post COVID-19 condition | > 4 months | mild | [18] | |
| with and without cognitive symptoms (e.g. "brain fog") | na | mainly mild | [93] | |
| Physical symptoms (e.g. arthralgia/myalgia, fatigue, cough), exertion intolerance | 12 months | severe | [80] | |
| e.g. fatigue, neurological, cardiopulmonary, gastrointestinal symptoms, trouble sleeping | ∼4 months | mild-severe | Peluso et al., 2022 | |
| Fatigue, cough, shortness of breath | 3–12 months | mild-severe | [85] | |
| One or more symptoms of the following e.g. pulmonary, systemic, neurological or psychiatric symptoms | 12 months | mild and moderate/severe | [83] | |
| Post-acute COVID-19 syndrome | different symptoms including fatigue, memory issues, loss of smell, abdominal pain | ∼7 months | mainly mild | [81] |