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Light scattering analysis of JEV TR RNA cyclization. (A) Multiple size exclusion chromatography runs associated with SEC-MALS. (B) MALS traces of each peak from the 5′ TR + 3′ TR run, and the absolute molecular weight across them. (C) Sedimentation distribution profiles of JEV 5′ TR and 3′ TR obtained from sedimentation velocity-analytical ultracentrifugation. Sedimentation coefficient values are corrected to standard solvent conditions (20 °C, water)
