Table 4.
Effects of CplR functionality on C. sporogenes resistance to nucleoside, PLSA and macrolide antibiotics
| MIC (μg/ml) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| C. sporogenes strain | erm | A201A | Hygromycin A | Retapamulin | Lincomycin | Clindamycin | Iboxamycin | Chloramphenicol | Erythromycin |
| JCM1416 wt | - | 1 | 4 | 25.6 | 32 | 16 | 0.125 | 2 | 0.5 |
| cplR::intron-ermB | c-ermB | 1 | 2 | 0.025 | 256 | 8 | 0.03125 | 2 | >256 |
| sigD::intron-ermB | c-ermB | 1 | 4 | 25.6 | 256 | 128 | 16 | 2 | >256 |
The MIC test for C. sporogenes was carried out in GAM media, and the growth inhibition was scored after 24 h of anaerobic incubation at 37°C.