Figure 6.

Obtaining two gene expression programs with a single TF is possible using promoters that are differently activated by TF dynamics. (A) Schematic representation of the construct. (B) Truth table showing the output of the circuit depending on synTF dynamics. 0 signifies low expression of the reporter protein; 1 signifies high expression of the reporter protein. (C) Bar plot showing the fold change in reporter expression for the indicated dynamics. The data represent the mean ± s.e.m of three biologically independent experiments.