Table 4.
Baseline level of Biochemical and inflammatory factors and Demographic and clinical characteristics of patients according to lymphopenia
| Biochemical and Inflammatory factors | Lymphopenia-Positive N = 52 |
Lymphopenia-Negative N = 73 |
P-value | ||||
|---|---|---|---|---|---|---|---|
| Cystatin C | 1.20 ± 0.45 | 1.58 ± 1.13 | 0.182 | ||||
| Creatinine | 1.19 ± 0.45 | 1.51 ± 1.04 | 0.216 | ||||
| Ferritin (Per 100) | 7.78 ± 4.42 | 5.16 ± 3.49 | 0.001 | ||||
| NLR | 9.72 ± 5.03 | 3.64 ± 1.20 | < 0.001 | ||||
| LDH (Per 100) | 7.27 ± 3.98 | 6.34 ± 2.39 | 0.468 | ||||
| CRP | 108.75 ± 66.55 | 76.69 ± 45.64 | 0.002 | ||||
| Demographic | |||||||
| Age | 63.50 ± 16.92 | 43.69 ± 16.94 | < 0.0011 | ||||
| Sex; n (%) | |||||||
| Male | 28(54) | 43(60) | 0.5742 | ||||
| Female | 24(46) | 30(40) | |||||
| Positive report for smoking | 14(27) | 29(40) | 0.1372 | ||||
| BMI | 27.95 ± 5.51 | 25.19 ± 5.11 | 0.0071 | ||||
| Positive report for comorbidities | |||||||
| Diabetic | 17(33) | 14(19) | 0.0852 | ||||
| Hypertension | 18(35) | 16(22) | 0.1162 | ||||
| Dyslipidemia | 18(35) | 16(22) | 0.1162 | ||||
| Cardiovascular disease | 20(38.50) | 9(12) | 0.0012 | ||||
| Asthma | 4(8) | 19(26) | 0.0092 | ||||
| COPD* | 16(31) | 23(31.50) | 0.9302 | ||||
| CKD** | 5(10) | 13(18) | 0.1982 | ||||
| Liver diseases | 6(11.50) | 7(10) | 0.7252 | ||||
*Chronic obstructive pulmonary disease; ** Chronic kidney disease; (1) Mann-Whitney test was used for comparison; (2) Chi-square test was used for comparison
NLR: neutrophil/lymphocyte ratio
CRP: C-reactive protein
LDH: Lactate dehydrogenase