TABLE 3.

Meta-analyses of the effects of probiotics compared with those of placebo on the duration of gastrointestinal tract infections (d/episode) in nonelderly adults

	Studies (n)	Mean difference (d/episode) (95% CI)	P	I2	P
ITT and CC analysis	4	0.26 (−0.22, 0.75)	0.29	0	0.86
ITTsanalysis1	3	0.15 (−0.29, 0.59)	0.50	0	0.77

CC, complete case; ITT, intention-to-treat assuming no cases among participants with missing data; ITTs, intention-to-treat assuming the risk ratio among participants with missing data matches the risk ratio of the control group from the CC analysis.

Random-effects meta-analysis using the inverse variance method by DerSimonian and Laird.

¹Does not include study 1 of Kollaritsch et al. [46] owing to missing information on the total number of participants enrolled.