TABLE 1.
The effect of soluble fiber supplements on blood lipids
| Variables | Pairwise meta-analysis |
Dose-response meta-analysis |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Studies, n | MD (95% CI) | P value | I2, % | Pheterogeneity | Dose, g/d | Studies, n | WMD (95% CI) | P value | I2, % | Pheterogeneity | |
| TG (mg/dL) | 208 | −5.55 (−10.31, −0.79) | 0.022 | 94.3 | <0.001 | 5 | 205 | −2.64 (−5.31, 0.03) | 0.052 | 94.8 | <0.001 |
| TC (mg/dL) | 214 | −10.82 (−12.98, −8.67) | <0.001 | 93.1 | <0.001 | 5 | 211 | −6.11 (−7.61, −4.60) | <0.001 | 94.7 | <0.001 |
| LDL cholesterol (mg/dL) | 199 | −8.28 (−11.38, −5.18) | <0.001 | 98.5 | <0.001 | 5 | 196 | −5.57 (−7.44, −3.69) | <0.001 | 98.4 | <0.001 |
| HDL cholesterol (mg/dL) | 207 | −0.03 (−0.45, 0.38) | 0.868 | 67.9 | <0.001 | 5 | 204 | 0.04 (−0.17, 0.26) | 0.693 | 65.6 | <0.001 |
| Apo-A (mg/L) | 31 | −10.47 (−31.16, 10.21) | 0.321 | 0.0 | 0.793 | 5 | 31 | −4.09 (−10.07, 1.89) | 0.180 | 0.0 | 0.830 |
| Apo-B (mg/L) | 35 | −44.99 (−62.87, −27.12) | <0.001 | 0.0 | 0.617 | 5 | 35 | −16.37 (−40.18, 7.42) | 0.177 | 86.8 | <0.001 |
Apo-A, apolipoprotein A; Apo-B, apolipoprotein B; MD, mean difference; TC; total cholesterol.