TABLE 2.
The effects of different doses of soluble fiber supplements on blood lipids form the nonlinear dose-response meta-analysis (mean difference and 95% CI)
| Soluble fiber supplements (g/d) | 0 (Reference) | 5 | 8 | 10 | 15 | 20 | 25 | 30 | 35 | 40 | 45 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| TG (mg/dL) | 0 | −4.89 (−9.14, −0.63) | −6.21 (−11.04, −1.39) | −6.63 (−11.33, −1.94) | −6.81 (−10.81, −2.82) | −6.73 (−11.30, −2.16) | −6.65 (−12.94, −0.35) | −6.56 (−15.07, 1.94) | −6.48 (−17.38, 4.42) | −6.40 (−19.79, 6.99) | −6.32 (−22.24, 9.61) |
| TC (mg/dL) | 0 | −49.71 (−118.49, 19.08) | −51.24 (−119.06, 16.59) | −44.14 (−99.23, 10.95) | −10.94 (−15.36, −6.53) | 26.82 (−35.31, 88.95) | 64.61 (−59.34, 188.55) | 102.39 (−83.41, 288.19) | 140.17 (−107.5, 387.83) | 177.94 (−131.59, 487.47) | 215.71 (−155.69, 587.11) |
| LDL−C (mg/dL) | 0 | −8.49 (−10.12, −6.85) | −10.39 (−12.29, −8.49) | −10.75 (−12.66, −8.83) | −9.89 (−11.77, −8.02) | −8.53 (−10.80, −6.26) | −7.16 (−10.16, −4.16) | −5.79 (−9.66, −1.92) | −4.42 (−9.24, 0.39) | −3.06 (−8.85, 2.74) | −1.69 (−8.49, 5.11) |
| HDL−C (mg/dL) | 0 | −0.09 (−0.73, 0.54) | −0.06 (−0.80, 0.69) | −0.00 (−0.75, 0.74) | 0.18 (−0.53, 0.89) | 0.38 (−0.42, 1.17) | 0.58 (−0.43, 1.59) | 0.78 (−0.51, 2.07) | 0.98 (−0.62, 2.58) | 1.18 (−0.75, 3.11) | 1.38 (−0.89, 3.65) |
| Apo−A mg/L | 0 | −4.25 (−24.52, 16.02) | −6.74 (−31.99, 18.51) | −8.38 (−34.82, 18.07) | −12.42 (−37.96, 13.12) | −16.43 (−41.93, 9.06) | −20.44 (−50.39, 9.50) | −24.45 (−61.93, 13.02) | −28.46 (−75.08, 18.15) | −32.47 (−89.06, 24.11) | −34.081 (−94.79, 26.64) |
| Apo−B mg/L | 0 | −49.37 (−75.91, −22.84) | −51.49 (−78.19, −24.76) | −44.93 (−72.34, −17.52) | −13.31 (−65.79, 39.18) | 22.85 (−65.94, 111.02) | 59.01 (−76.21, 194.22) | 95.16 (−83.31, 273.64) | 131.32 (−90.71, 353.34) | 167.47 (−98.25, 433.19) | 181.941 (−101.29, 465.16) |
Apo-A, apolipoprotein A; Apo-B, apolipoprotein B; TC; total cholesterol.
1
42 g of soluble fiber supplement.