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. 2023 May 22;12:27. doi: 10.1186/s40035-023-00356-y

Table 2.

Correlation of cortical thickness signature with clinical parameters in derivation samples of age-matched DLB and healthy controls

DLB-pattern AD-pattern Mean cortical thickness
Correlation coefficient P value Correlation coefficient P value Correlation coefficient P value
MMSE − 0.31 0.035 − 0.088 0.55 0.37 0.011
Cognition (MDS-UPDRS part I) 0.051 0.79 0.17 0.41 − 0.64 4.18 × 10–4
MDS-UPDRS part I  − 0.042 0.92 0.12 0.52 − 0.45 0.017
MDS-UPDRS part II  0.041 0.90 − 0.16 0.42 − 0.52 0.0045
MDS-UPDRS part III  0.051 0.87 0.24 0.26 − 0.58 0.0029
Digit span test − 0.11 0.58 0.22 0.28 0.053 0.80
TMT-A − 0.55 0.024 − 0.081 0.79 0.058 0.84
CWST − 0.24 0.32 − 0.26 0.35 − 0.11 0.69
BNT − 0.35 0.062 − 0.095 0.65 0.48 0.013
RCFT − 0.54 0.0047 − 0.19 0.38 0.33 0.12
SVLTi − 0.11 0.56 − 0.065 0.75 0.37 0.060
SVLTd − 0.25 0.18 − 0.089 0.66 0.32 0.10
SVLTr − 0.16 0.41 0.14 0.49 0.50 0.0078
COWAT 0.083 0.73 0.38 0.16 − 0.028 0.92
TMT-B − 0.56 0.036 − 0.29 0.33 0.24 0.41

Age and sex were included as cofactors for correlation analysis between cortical thickness pattern score and clinical variables MDS-UPDRS part I (except for cognition subscore), II and III. Age, sex and education year were included as cofactors in the correlation analysis between cortical thickness patterns and cognitive profiles (Cognition subscore from MDS-UPDRS part I and scores from neuropsychological tests)

The significant values (P < 0.05) are shown in bold

BNT Boston Naming Test, COWAT Controlled Oral Word Association Test, CWST Korean Color Word Stroop Test, DLB Dementia with Lewy bodies, MDS-UPDRS Movement Disorders Society-Unified Parkinson Disease Rating Scale, RCFT Rey Complex Figure Test copy, SVLT Seoul Verbal Learning Test, TMT Trail Making Test