Table 3.

Correlations of cortical thickness signature scores at baseline with clinical parameters at baseline and at 4-year follow-up in iRBD

	DLB-pattern				AD-pattern				Mean cortical thickness
	Baseline		4-year progression		Baseline		4-year progression		Baseline		4-year progression
	Correlation coefficient	P	Correlation coefficient	P	Correlation coefficient	P	Correlation coefficient	P	Correlation coefficient	P	Correlation coefficient	P
B-SIT	− 0.14	0.40	N.A	N.A	− 0.19	0.24	N.A	N.A	0.039	0.21	N.A	N.A
Cognition*	− 0.017	0.91	0.026	0.92	0.23	0.13	0.19	0.44	− 0.086	0.57	0.054	0.83
MDS-UPDRS part I	0.14	0.36	− 0.28	0.28	0.27	0.069	− 0.19	0.44	− 0.11	0.46	− 0.31	0.20
MDS-UPDRS part II	0.13	0.39	− 0.11	0.67	0.27	0.065	0.15	0.55	− 0.11	0.47	− 0.19	0.45
MDS-UPDRS part III	0.08	0.56	− 0.044	0.25	0.16	0.29	0.33	0.17	− 0.18	0.23	− 0.26	0.28
Digit span test	− 0.32	0.033	0.29	0.61	− 0.036	0.82	0.064	0.81	− 0.039	0.80	0.10	0.70
TMT-A	− 0.21	0.21	0.13	0.067	− 0.12	0.47	0.057	0.83	− 0.084	0.61	0.33	0.21
CWST	0.31	0.075	− 0.43	0.31	− 0.11	0.54	− 0.41	0.12	0.11	0.54	− 0.13	0.62
BNT	0.042	0.79	− 0.23	0.37	− 0.019	0.90	− 0.22	0.37	− 0.26	0.082	− 0.088	0.72
RCFT	− 0.067	0.68	− 0.22	0.035	0.17	0.26	− 0.34	0.17	− 0.22	0.16	− 0.0062	0.98
SVLTi	0.073	0.65	− 0.46	0.018	0.25	0.097	− 0.46	0.048	0.080	0.60	− 0.085	0.73
SVLTd	0.061	0.70	− 0.51	0.068	0.12	0.42	− 0.60	0.007	0.16	0.29	− 0.44	0.057
SVLTr	− 0.073	0.64	− 0.41	0.54	0.18	0.25	− 0.24	0.33	− 0.17	0.27	0.23	0.35
COWAT	0.067	0.68	− 0.16	0.54	0.0076	0.96	− 0.19	0.49	0.022	0.89	0.11	0.69
TMT-B	0.25	0.13	− 0.002	0.99	0.10	0.58	0.32	0.24	− 0.052	0.78	0.29	0.29

Age and sex were included as cofactors for correlation analysis between cortical thickness signature scores (DLB-pattern, AD-pattern and mean cortical thickness) and clinical variables (SIT, MDS-UPDRS part I, II and III). Age, sex and education year were included as cofactors in the correlation analysis between cortical signature scores with cognitive profiles (Cognition* from MDS-UPDRS part I subscore and scores from neuropsychological tests)

The significant values (P < 0.05) are shown in bold

B-SIT Brief smell identification test, BNT Boston Naming Test, COWAT Controlled Oral Word Association Test, CWST Korean Color Word Stroop Test, SIT Smell identification test, MDS-UPDRS Movement Disorders Society-Unified Parkinson Disease Rating Scale, TMT Trail Making Test, RCFT Rey Complex Figure Test copy, SVLTi SVLTd, SVLTr: immediate recall, delayed recall and recognition in Seoul Verbal Learning Test, respectively. N.A. Not Applicable