Table 1.
Mutations in genes of MT strain
| Gene | Product | DNA changes | Protein changes | Karyotic |
|---|---|---|---|---|
| AGOS_AAL021W | Small subunit of acetohydroxyacid synthase (AgILV6) | c.140G > A | p.S47N | Hetero |
| AGOS_AAL021W | Small subunit of acetohydroxyacid synthase (AgILV6) | c.155G > A | p.S52N | Hetero |
| AGOS_AAL021W | Small subunit of acetohydroxyacid synthase (AgILV6) | c.673G > T | p.G225C | Hetero |
| AGOS_ACR052W | Flavoprotein subunit of succinate dehydrogenase (AgSDH1) | c.1132G > A | p.D378N | Hetero |
| AGOS_ACL065C | Iron-sulfur protein subunit of succinate dehydrogenase (AgSDH2) | c.224C > T | p.T75M | Hetero |
| AGOS_ACL065C | Iron-sulfur protein subunit of succinate dehydrogenase (AgSDH2) | c.697A > C | p.T233P | Hetero |
| AGOS_AEL305C | Acetohydroxyacid synthase (AgILV2) | c. 1365G > T | p.Q455H | Homo |
| AGOS_AFR447C | NADH:ubiquinone oxidoreductase (AgNDI1) | c.943G > A | p.V315M | Hetero |
| AGOS_AGR196W | Glutathione-disulfide reductase (AgGLR1) | c.1415C > A | p.S472Y | Hetero |