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. 2023 May 22;23:173. doi: 10.1186/s12871-023-02120-1

Table 4.

Individual effect of OPRM1 A118G on VAS of PACU

Exposure Non-adjusted Adjust model I Adjust model II
OR(95%CI) P Value OR(95%CI) P Value OR(95%CI) P Value
OPRM1 A118G
 GG 1.0 1.0 1.0
 GA + AA 14.73 (3.21, 67.49) 0.001 16.55 (3.01, 91.15) 0.001 19.94 (3.14, 126.82) 0.002

Adjustment model I: adjusted according to age, sex, weight, height, and operation duration

Adjustment model II: adjusted according to age, sex, weight, height, operation duration and the polymorphisms of CYP3A4 *1G、CYP3A5 *3 and COMT Val158Met polymorphisms