Table 2.
NHANES 1976–80 Ulcerative Colitis Clinical Data.
| Ulcerative Colitis | No Ulcerative Colitis | ||||
|---|---|---|---|---|---|
| n | % (95% CI) | n | % (95% CI) | p value | |
| Self-Reported Health Status | |||||
| Good, Excellent | 96 | 63.6 (53.7,73.4) | 11,528 | 81.5 (80.0,83.0) | <0.01 |
| Fair, Poor | 75 | 36.5 (26.6,46.4) | 3637 | 18.5 (17.0,20.1) | <0.01 |
| Illness Now Affects Digestion/Appetite | 63 | 31.3 (22.0,40.6) | 1772 | 10.5 (9.7,11.3) | <0.01 |
| Illness is Colitis | 26 | 13.5 (7.0,20.1) | 184 | 1.0 (0.8,1.2) | <0.01 |
| Current Gastrointestinal Symptoms: | |||||
| Overall GI Symptoms: | 94 | 67.4 (56.8,78.0) | 2852 | 23.2 (22.0,24.4) | <0.01 |
| Diarrhea | 37 | 29.5 (20.2,38.9) | 638 | 5.9 (5.2,6.6) | <0.01 |
| Constipation | 35 | 15.0 (7.6,23.4) | 1820 | 13.7 (12.4,14.9) | 0.73 |
| Detailed Distribution: | |||||
| Only Diarrhea | 34 | 25.7 (17.1,34.4) | 1791 | 4.2 (3.7,4.8) | <0.01 |
| Only Constipation | 32 | 17.0* | 585 | 10.6 (9.7,11.6) | n.a. |
| Both Diarrhea and Constipation | 3 | 1.9 * | 146 | 1.0 (0.8,1.2) | n.a. |
| Neither Diarrhea nor Constipation | 67 | 55.4 (44.0,66.8) | 11,666 | 84.2 (83.0,85.3) | <0.01 |
| Loss of Blood Stomach or Bowels | 37 | 26.5 (15.9,37.2) | 422 | 3.5 (3.0,3.9) | <0.01 |
| Gray Stools | 3 | 1.9* | 83 | 0.6 (0.4,0.8) | n.a. |
| Melena | 25 | 17.1* | 605 | 4.8 (4.2,5.4) | n.a. |
| Blood-streaked Stools | 36 | 35.2 (24.7,45.7) | 618 | 5.4 (4.9,5.9) | <0.01 |
| Overall Medical Therapy: | 106 | 65.2 (54.6,75.8) | 5585 | 36.4 (35.2,37.5) | <0.01 |
| Any Current Prescription Medication | 115 | 60.5 (51.1,69.9) | 5682 | 32.3 (31.4,33.3) | <0.01 |
| Regular ASA or ASA-Like Med Use | 72 | 38.8 (28.6,49.0) | 4118 | 25.9 (24.8,27.0) | 0.02 |
| Diagnosed Anemia | 55 | 44.1 (32.7,55.5) | 2190 | 15.9 (15.0,16.8) | <0.01 |
| Had Iron Therapy for Anemia | 47 | 37.2 (24.4,50.0) | 1745 | 12.9 (12.1,13.7) | <0.01 |
| Current Anemia Therapy | 9 | 8.4* | 276 | 1.8 (1.6,2.1) | n.a. |
| Overall Hospital Treatment History: | 54 | 36.5 (25.4,44.7) | 2443 | 15.0 (14.2,15.8) | <0.01 |
| Hospitalized in Last 12 Months | 42 | 26.3 (16.3,36.2) | 2260 | 13.7 (12.9,14.5) | 0.01 |
| Reason is GI Disorder | 6 | 5.0* | 72 | 0.4 (0.2,0.5) | n.a. |
| History of Transfusion | 13 | 11.0* | 263 | 1.9 (1.5,2.2) | n.a. |
| Abdominal Surgery | 85 | 52.7 (38.4,67.1) | 4323 | 35.3 (33.9,36.6) | 0.02 |
| Disease Associations | |||||
| Diagnosis of Arthritis | 89 | 38.7 (28.2,49.2) | 3756 | 20.3 (19.2,21.4) | <0.01 |
| Any Cancer Diagnosis | 14 | 5.9* | 603 | 3.4 (3.1,3.7) | n.a. |
| Diagnosis Spastic Colon/Mucous Colitis | 54 | 31.8 (21.9,41.8) | 500 | 3.3 (2.8,3.8) | <0.01 |
Abbreviations: n = sample size; 95 %CI = 95% confidence interval; ASA = aspirin; n.a. = not applicable.
Notes: Mobile exam center interview adult target age range was 25 to 74 years. Item samples sizes vary by data collection location: household interview (15,357); mobile exam center interview (current gastrointestinal symptoms 11,854; physician exam, abdominal surgical scar (11,854). *Variance estimate not statistically reliable.