Table 1.

Main immune system factors that promote target organs damage during SAH.

Organ	Immune Factor Involved
Blood vessels	T-cell activation produces pro-inflammatory cytokines (IFN-γ, TNF-α, IL-17A) Monocytes
Kidney	T-cell activation secrets IL-6, IL-1β, IFN-γ, TNF-α, IL-17A M1-type macrophages Dendritic cells Toll-like receptors
Heart	T-lymphocytes, neutrophils, macrophages IL-17, IL-23, TNF-α
Brain	T-cells increase Cerebral perivascular macrophages IL-1β

IFN-γ = Interferon-gamma; TNF-α = Tumor necrosis factor-α; IL = interleukin