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. 2023 May 22;8(8):1506–1513. doi: 10.1016/j.ekir.2023.05.010

Table 2.

Characteristics of patients with COVID-19 or SARS-CoV-2 vaccination associated TMA

TMA diagnosis
Patien number Sex Age Event Time to TMA from eventb Native kidney; kindey graft SCr PLT LDH UPCR Kidneybiopsy TMA treatment Outcome3 mo
7a M 34 COV 44 G 6.28 207 252 4746 active TMA 5× PLEX SCr 6.78
9a F 32 COV 28 G 1.54 355 203 3425 TMA vs. ABMR on antiC5 SCr 1.66
24a F 21 COV 16 N 18.96 124 422 n.a. n.a. anti C5 chronic HD
27a M 67 VAC 10 G 2.54 132 277 3246 relapsing TMA antiC5 SCr 2.63

ABMR, antibody mediated rejection; anti C5, eculizumab or ravulizumab therapy; CFH, complement factor H; COV, coronavirus disease 19; F, female; G, kidney graft; HD, hemodialysis; LDH, lactate dehydrogenase (reference range: <250 U/l); M, male; N, native kidney; n.a., not available; PLEX, plasma exchange; PLT, platelet count (reference range: 150-350 G/L); SCr, serum creatinine in mg/dl; TMA, thrombotic microangiopathy; UPCR, urinary protein to creatinine ratio (reference range: <200 mg/g); VAC, SARS-CoV-2 vaccination.

a

TMA relapse.

b

In days.