FIG. 6.
Change in microtubule separation with varying crosslinker number. (a) Schematic of the model. The microtubule separation h varies due to forces from crosslinkers. (b) Plot of free energy as a function of microtubule separation for 13-site microtubules with 4 32-nm-long crosslinkers, from semi-analytic theory. (c) Probability as a function of microtubule separation for 13-site microtubules with 4 32-nm-long crosslinkers from semi-analytic theory (red) and simulation (blue). (d) Average microtubule separation as a function of number of crosslinkers for 13-site microtubules, comparing full semi-analytic theory (red), simulation (blue), and theory neglecting steric exclusion (green) and both steric exclusion and discrete lattice sites (gold). (d) Average microtubule separation as a function of number of crosslinkers for 100-site microtubules.