Table 5. Multivariable Cox proportional analysis of BMs patients with BED.
The OS of patients with different BED10 is shown.
| Variables | Multivariable analysis | P-value | |
|---|---|---|---|
| HR (95% CI) | |||
| Age | 1.02 (1.01–1.02) | <0.01 | |
| Biologically Effective dose (BED10: Gy) | SRS <55 | Ref | |
| SRS >= 55 | 0.99 (0.94–1.06) | 0.97 | |
| SRT <55 | 0.93 (0.86–1.01) | 0.07 | |
| SRT >= 55 | 1.16 (0.94–1.43) | 0.18 | |
| Sex | Male | Ref | |
| Female | 0.82 (0.77–0.86) | <0.01 | |
| Race | White | Ref | |
| Black | 0.91 (0.83–0.99) | 0.04 | |
| Other | 0.75 (0.65–0.87) | <0.01 | |
| Education | >=13% NHSD | NS | 0.24 |
| <13% NHSD | Ref | ||
| Income | >=$35,000 | Ref | |
| <35,000 | 1.11 (1.05–1.18) | <0.01 | |
| Place of Living | Urban | Ref | |
| Rural | … | ||
| Hospital Type | Academic | Ref | |
| Community | 1.08 (1.02–1.14) | 0.01 | |
| Insurance Status | Yes | Ref | |
| No | … | ||
| Charlson/Deyo Score | 0 | Ref | |
| 1 | 1.14 (1.07–1.22) | <0.01 | |
| >=2 | 1.21 (1.11–1.32) | <0.01 | |
| Chemotherapy | Yes | ref | |
| No | 1.70 (1.60–1.81) | <0.01 | |
| Primary Cancer | Breast | 0.62 (0.49–0.77) | <0.01 |
| NSCLC | 0.78 (0.68–0.90) | <0.01 | |
| SCLC | 0.98 (0.80–1.19) | 0.81 | |
| Other Lung | 0.97 (0.80–1.19) | 0.80 | |
| Melanoma | 0.46 (0.38–0.55) | <0.01 | |
| CRC | 1.00 (0.74–1.35) | 0.98 | |
| Renal Cell | Ref | ||
| Year of Diagnosis | 2010–2013 | 1.10 (1.04–1.17) | <0.01 |
| 2014–2015 | Ref | ||
Notes.
- Trt
- treatment
- NHSD
- no high school degree
Variable had p > 0.15 in univariable analysis and was not included in the multivariable analysis.