Mori 2000.

Study characteristics
Methods	Study type: RCT Aim of the study: efficacy Participating sites: 1 university hospital in Sapporo, Japan Language: English
Participants	Number randomised: 36 (intervention); 18 (control) Inclusion criteria: people successfully resuscitated from out‐of‐hospital cardiac arrest with GCS < 8 Mean age: n.i. Women (%): n.i. Cardiac arrest location: out‐of‐hospital Cause of cardiac arrest: n.i. Primary cardiac rhythm: n.i. Witnessed cardiac arrest: n.i. Bystander CPR: n.i. Timing (minutes): n.i. Temperature on admission/at start of cooling: n.i. Subgroups reported: none
Interventions	Prehospital cooling: no Target temperature: 32–34 °C Duration (hours) of cooling: 72 hours Was intervention initiated within 2 hours of ROSC? n.i. Was target temperature reached within 4 hours of ROSC? n.i. Co‐interventions? n.i. Was rewarming controlled? n.i. Rewarming rate (per protocol): n.i. Description of intervention: water‐circulating blankets above and below participant with another ice‐mounted blanket over participant Cooling rate: n.i. Timing of intervention: n.i.
Outcomes	GCS at 1 month (5‐point scale). Categories "moderate, mild, or no disabilities" defined as "good neurological outcome."
Control group treatment	Brain normothermic therapy at 36 °C
Funding source
Notes	Abstract Study included in the pooled analysis, as we received information from the authors on the cooling method