Table 1.
Fitness browser: conditions leading to strong fitness defects in an Escherichia coli BW25113 ΔyggS mutant
|
Experimental condition |
Fitness score |
t-value |
|---|---|---|
|
M9 0.4 % glucose 2.5×4dPN/PN challenge (250 nM/100 nM) |
−6.23 |
−6.06 |
|
M9 0.4 % glucose 250×4dPN/PN challenge (25 µM/100 nM) |
−6.11 |
−5.95 |
|
M9 0.4 % glucose 12.5×4dPN/PN challenge (250 nM/20 nM) |
−5.84 |
−6.94 |
|
M9 0.4 % glucose 5×4dPN/PN challenge (25 µM/5 µM) |
−4.96 |
−7.56 |
|
Outer cut, LB soft agar motility assay |
−4.9 |
−5.1 |
|
2-Furfuraldehyde (0.25 vol%) |
−3.0 |
−3.5 |
|
l-Malic acid (carbon source) |
−2.0 |
−3.8 |
*For conditions with multiple strong fitness defect scores, the strongest score and relevant t-value statistic are shown* https://fit.genomics.lbl.gov/cgi-bin/singleFit.cgi?orgId=Keio&locusId=17030&showAll=0
4dPN, 4'-deoxypyridoxine; PN, pyridoxine.