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. 2023 May 5;6:0086. doi: 10.34133/research.0086

Fig. 1.

Fig. 1.

Local rapid release of PDGF-BB has no obvious osteogenesis effect on critical bone defect. (A) The reconstructions of representative calvarial models (average of the individual samples) measured by micro-CT. Original defect area is shaded with a dashed outline (control, black; PDGF-BB [1.0 ug], red). (B) The quantitative analysis of micro-CT reconstruction of CSD model (control, black; PDGF-BB, red). Data are means ± standard error of the mean (SEM). n = 5 or 6. Student t test. ns P ≥ 0.05. (C and E) The H&E staining image of each group (control, dotted line; PDGF-BB, full line). Scale bar, 50 μm. (D and F) The Masson staining of each group (control, dotted line; PDGF-BB, full line). Scale bar, 50 μm. BS, bone surface; BV, bone volume; BMD, bone mineral density; TV, tissue volume; Tb.Th, trabecular thickness; Tb.Sp, trabecular separation.