Table 1.
Demographic and clinical characteristics and findings on investigations
| Clinical characteristics | Patient 1 | Patient 2 | Patient 3 | Patient 4 |
|---|---|---|---|---|
| Age, years | 13 | 14 | 14 | 14 |
| Sex | Male | Male | Female | Female |
| History of contact | Present | Absent | Absent | Absent |
| Comorbidities | No | Type 1 DM | No | No |
| Time to presentation, days | 5 | 6 | 10 | 7 |
| Disease severity | Severe | Mild | Mild | Severe |
| Body temperature, °F | 102.3 (↑) | 101.3 (↑) | 100.4 (↑) | 101.7 (↑) |
| Respiratory rate, per min | 32 (↑) | 30 (↑) | 22 (N) | 28 (↑) |
| Heart rate, per min | 130 (↑) | 110 (↑) | 108 (↑) | 118 (↑) |
| Blood pressure, mm Hg | 80/60 (↓) | 100/60 (N) | 90/60 (N) | 70/40 (↓) |
| SpO2 on RA, % | 85 (↓) | 95 (N) | 99 (N) | 83 (↓) |
| COVID-19 RT-PCR | Negative | Negative | Negative | Negative |
| COVID-19 IgG titer, U/mL | 250 (↑) | 131 (↑) | 88 (↑) | 72 (↑) |
| Hb levels, g/dL | 12.4 (N) | 9.9 (↓) | 10 (↓) | 10.7 (↓) |
| Leucocyte count, cells/µL | 15700 (↑) | 16300 (↑) | 1700 (N) | 5400 (N) |
| Platelets, cells/µL | 95000 (↓) | 151000 (N) | 71000 (↓) | 97000 (↓) |
| Neutrophils, cells/µL | 20.8 (↑) | 80 (↑) | 56 (↑) | 83 (↑) |
| Lymphocytes, cells/µL | 9.16 (↑) | 16 (↑) | 38 (↑) | 11.3 (↑) |
| C-reactive protein, mg/L | 110 (↑) | 107.9 (↑) | 84.1 (↑) | 123 (↑) |
| ESR, mm/hour | 54 (↑) | 60 (↑) | 47 (↑) | 56 (↑) |
| Procalcitonin, ng/mL | 0.10 (↑) | 0.16 (↑) | 0.08 (N) | 0.12 (↑) |
| LDH, IU/L | 352 (↑) | 888 (↑) | 628 (↑) | 560 (↑) |
| D dimer, µg/L | 4060 (↑) | 9640 (↑) | 2633 (↑) | 1300 (↑) |
| INR | 1.44 (↑) | 1.21 (↑) | 1.1 (N) | 1.12 (N) |
| Fever profile | Negative | Negative | Negative | Negative |
| Blood culture | Negative | Negative | Negative | Negative |
| Urine culture | Negative | Negative | Negative | Negative |
| Liver function test | WNL | WNL | WNL | WNL |
| Renal function test | WNL | WNL | WNL | WNL |
| X-Ray chest | WNL | WNL | WNL | WNL |
| HRCT chest | WNL | WNL | ND | ND |
| ECG | Sinus Tachycardia | Sinus Tachycardia | Sinus Tachycardia | Sinus Tachycardia |
| 2D ECHO | WNL | WNL | Mild global hypokinesia | Biventricular dysfunction, mild pericardial effusion |
| Hospital stay, days | 2 | 10 | 7 | 10 |
SpO2 on RA, oxygen saturation on room air; RT-PCR, real-time polymerase chain reaction; Ab, antibody; Hb, hemoglobin; ESR, erythrocyte sedimentation rate; LDH, lactate dehydrogenase; INR, international normalization ratio; Fever profile, malaria, dengue, Scrub Typhus, and Leptospira; WNL, within normal limits; HRCT Chest, high-resolution computed tomography of chest; ND, not done; ECG: electrocardiography; 2D ECHO, Two-dimensional echocardiography; ↑, increased; ↓, decreased; N, normal; ND, not done.