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. Author manuscript; available in PMC: 2023 May 22.
Published in final edited form as: Neurosci Biobehav Rev. 2019 Nov 19;108:435–444. doi: 10.1016/j.neubiorev.2019.11.007

Table 1.

Pathways with overlapping roles in motivational responses to cues and the effects of sleep deprivation on reward-related behavior.

Pathways Role in motivation Effect of sleep deprivation References
VTA – NAcc – VP Attribution of incentive salience to cues (STs > GTs) Hyperactivity and enhanced reward seeking Flagel et al., 2017;
Satterfield et al., 2019
PFC – PVT – NAcc Predictive value of reward-paired cues (GTs > STs) Weakened inhibitory control over reward seeking Haight et al., 2017;
Liu et al., 2016
AMG – NAcc Amplification of conditioned responding without changing the target of approach Increase in the subjective valuation of food cues DeFeliceantonio and Berridge 2012;
Rihm et al., 2018