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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Mol Genet Metab. 2023 Apr 15;139(1):107584. doi: 10.1016/j.ymgme.2023.107584

Fig. 3. Linear modeling of phenotypic features by MRS metabolite, controlling for age and genotype.

Fig. 3

The slope of metabolite (i.e., expected change in behavior score for each one-unit change in metabolite difference from normative value) is plotted with its 95% confidence interval; where the 95% confidence interval does not include zero the slope marker is white filled. ABC: adaptive behavior composite. CGI: clinician global impression of change. Glx: Glu+Gln+GABA. NAA: N-acetyl aspartic acid. PGM: parietal gray matter. Physical, Capability, CGI: Unified Batten Disease Rating Scale sub-domains. VIQ: verbal intelligence quotient.