Table 1.

Plasma cytokine/chemokine levels

	Male		Female		P Value
Cytokine	Young	Old	Young	Old	Age	Sex	Interaction
IFN-γ	1,006 ± 607	2,128 ± 1,301	1,626 ± 1,033	2,432 ± 2,276	0.0373	0.3081	0.7264
IL-1β	354 ± 43	463 ± 114	516 ± 194	415 ± 135	0.9166	0.1953	0.0203
IL-6	2,970 ± 724	6,320 ± 3,132	2,794 ± 572	8,261 ± 4,197	<0.0001	0.3162	0.2309
MCP-1	727 ± 134	1,088 ± 526	891 ± 131	1,427 ± 855	0.0121	0.1489	0.6118
TNF-α	583 ± 171	603 ± 165	648 ± 114	610 ± 176	0.4700	0.8624	0.5581

Values are means ± SD (n = 9–13/group) and are expressed as arbitrary units of intensity relative to an internal positive control. Plasma was analyzed by cytokine array. IFN-γ, interferon-γ; IL-1β, interleukin-1β; IL-6, interleukin 6; MCP-1, monocyte chemoattractant protein-1; TNF-α, tumor necrosis factor-α. Statistics are two-way mixed (age × sex) ANOVA with Sidák’s post hoc test. Boldface indicates significant value.