Table 3.
Changes in IFN regulated gene expression following NR2F2 silencing in various types of endothelial cells
LMVEC |
CAEC |
PAEC |
EA.hy926 |
|||||
---|---|---|---|---|---|---|---|---|
Gene Symbol | Fold-Changea | P Value | Fold-Changea | P Value | Fold-Changea | P Value | Fold-Changea | P Value |
CCL5 | 10.0 | <0.001 | 3.2 | <0.001 | 3.9 | 0.012 | 3.5 | <0.001 |
CCL7 | 7.8 | <0.001 | 3.2 | 0.026 | 2.3 | 0.052 | 2.7 | <0.001 |
CD40 | 1.5 | 0.006 | 1.9 | <0.001 | 1.8 | 0.002 | NT | |
CD274 | 2.5 | 0.005 | 1.9 | 0.003 | 1.5 | 0.230 | 2.0 | <0.001 |
CXCL10 | 15.7 | <0.001 | 6.6 | <0.001 | 3.0 | 0.028 | 0.8 | 0.002 |
CXCL11 | 5.4 | <0.001 | 4.5 | 0.002 | 0.6 | 0.002 | 3.2 | <0.001 |
IFITM1 | 1.5 | <0.001 | 2.6 | 0.001 | 1.3 | 0.346 | 4.7 | <0.001 |
Results are shown as fold changes of siNR2F2 vs. siCTRL. LMVEC, lung microvascular endothelial cell; CAEC, coronary artery endothelial cell; PAEC, pulmonary artery endothelial cell; NT, not tested, P < 0.05 bolded.