Table 2.
The differences in parameters between patients with VT resulting in ATP vs. patients without VT resulting in ATP during follow-up
Proposed risk factors | VT resulting in ATP n = 15 | No VT resulting in ATP n = 31 | P-value |
---|---|---|---|
Age mean ± SD | 55.5 ± 13.3 | 53.2 ± 11.4 | 0.59 |
Age at diagnosis mean ± SD | 41.6 ± 13.8 | 40.2 ± 12.0 | 0.35 |
Male n (%) | 11 (73.3) | 17 (54.8) | 0.34 |
Diabetes mellitus n (%) | 0 (0) | 3 (9.7) | 0.54 |
Hypertension n (%) | 5 (33.3) | 8 (25.8) | 0.73 |
Ischaemic heart disease n (%) | 1 (6.7) | 0 (0) | 1.00 |
Atrial fibrillation n (%) | 2 (13.3) | 6 (19.4) | 0.33 |
Bundle branch block n (%) | 2 (13.3) | 7 (22.6) | 0.70 |
Anti-arrhythmic drugs n (%) | 10 (66.7) | 18 (58.1) | 0.75 |
Sotalol n (%) | 8 (80.0) | 10 (55.6) | 0.21 |
Flecainide n (%) | 2 (20.0) | 3 (16.7) | 1.00 |
Amiodarone n (%) | 0 (0) | 5 (27.8) | 0.16 |
Left ventricular function ≥55% n (%) | 8 (53.3) | 16 (51.6) | 1.00 |
Left ventricular involvement n (%) | 7 (46.7) | 15 (48.4) | 1.00 |
Severe ventricular impairment n (%) | |||
RV function n (%) | 12 (80.0) | 1 (3.2) | <0.001 |
LV function n (%) | 3 (20.0) | 4 (12.9) | 0.67 |
Severely ventricular dilatation n (%) | <0.001 | ||
RV size n (%) | 9 (60.0) | 3 (9.7) | <0.001 |
LV size n (%) | 2 (13.3) | 2 (6.5) | 0.59 |
Right ventricle aneurysm n (%) | 1 (6.7) | 1 (3.2) | 1.00 |
Gene status n (%) | 14 (93.3) | 21 (67.7) | 0.07 |
DSP n (%) | 2 (14.3) | 11 (52.4) | 0.03 |
PKP2 n (%) | 10 (71.4) | 3 (14.3) | 0.001 |
DSP, desmoplakin; LV, left ventricle; PKP2, plakophilin 2; RV, right ventricle.