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PGF2α production is stimulated by crystalline silica (CS) and amorphous silica (AS). Fibroblasts were exposed to indicated doses of CS and AS. MC, untreated media control. The cell supernatants were harvested after 48 h and analyzed for PGF2α using enzyme immunoassays. The increase in PGF2α production is statistically significant (*p<0.01).
